Abstract: |
Introduction: The assessment of muscle tone is an integral part of the routine neuromotor evaluation of infants. It is generally known that many infants show one or two signs of atypical neuromotor performance, but only an aggregation of multiple signs of atypical neuromotor performance is associated with an increased risk of neurodevelopmental disorder. We addressed the muscle tone disorders in infants and described their functional characteristics as follows: lowered (hypotonia), increased (hypertonia), changing muscle tone, and normal of a central etiology that happens to emerge antenatally, intrapartum, or postnatally. Muscle tone disorders are often represented in the so-called “risky children” (children who were exposed to one or more risk factors for neurodevelopmental disorders in their medical history), and those can be an implication of a primary disorder of the central nervous system in terms of a prior brain lesion.
Aim: To investigate if there is a difference in the age at the first infants' examination in pediatric physiatrist outpatient settings due to muscle tone disorders categorization.
Methods: The study enrolled 179 infants of both genders assessed by a pediatric physiatrist in outpatient settings upon first examination (AS±SD: age 158,36±110,91 days; weight 3267,78±708,69 g; and length of 49,33±3,09 cm) due to muscle tone disorders with the presence of mild and moderate neurodevelopmental disorder as sequelae of immature brain impairment. Conducting this case study was approved by the Ethical Committee of Sestre milosrdnice University Hospital Center in February 2022 identified by code number 003/-06/22-03/003. Written informed consent was obtained from parents whose infants participated in this case study.
Results: Infants diagnosed with increased muscle tone appear to be earlier referred from primary care to a pediatric physiatrist examination (AS±SD:115,68±51,86 days, compared to average total AS±SD:158,36±110,91 days). The main findings confirm statistically significant differences between infants differently categorized by muscle tone and infant’s age at the first examination (AFE) - among those with hypertonia and those with hypotonia (AFE: p=0,00; GA+ AFE: p<0,01) as well among hypertonia and changing muscle tone respectively (AFE: p=0,00; GA+ AFE: p<0,01).
Conclusion: According to the average AFE (Mean±SD:158,36±110,91 for the whole sample, Mean±SD:151,34±127,59 for normal muscle tone) within hypertone infants a deviation is presented (Mean±SD: 115,67±51,86), which cumulatively with gestational age (Mean±SD:387,275±55,38) presents valid information to be furtherly analyzed. Muscle tone disorders in terms of hypotonia, hypertonia, and changing muscle tone are considered to be symptomatic risk and it stands in need of proper and prompt habilitation treatment, even though spontaneous normalization is often achievable. |